James C Barton Selected Research

Ferritins (Ferritin)

6/2022	HLA-A*03, the hemochromatosis ancestral haplotype, and phenotypes of referred hemochromatosis probands with HFE p.C282Y homozygosity.
1/2021	Abdominal pain and cirrhosis at diagnosis of hemochromatosis: Analysis of 219 referred probands with HFE p.C282Y homozygosity and a literature review.
1/2019	Pagophagia in men with iron-deficiency anemia.
1/2017	Diabetes in HFE Hemochromatosis.
3/2016	Risk Factors for Insulin Resistance, Metabolic Syndrome, and Diabetes in 248 HFE C282Y Homozygotes Identified by Population Screening in the HEIRS Study.
1/2016	Undiagnosed diabetes and impaired fasting glucose in HFE C282Y homozygotes and HFE wild-type controls in the HEIRS Study.
5/2015	Serum ferritin is a biomarker for liver mortality in the Hemochromatosis and Iron Overload Screening Study.
3/2015	Serum ferritin, insulin resistance, and metabolic syndrome: clinical and laboratory associations in 769 non-hispanic whites without diabetes mellitus in the HEIRS study.
7/2013	HFE mutations in Caucasian participants of the Hemochromatosis and Iron Overload Screening study with serum ferritin level <1000 µg/L.
6/2012	Probability of C282Y homozygosity decreases as liver transaminase activities increase in participants with hyperferritinemia in the hemochromatosis and iron overload screening study.

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James C Barton Research Topics

Disease

58	Hemochromatosis (Bronze Diabetes) 06/2022 - 10/2002
54	Iron Overload 06/2022 - 02/2003
18	Fibrosis (Cirrhosis) 06/2022 - 04/2003
10	Hyperferritinemia 08/2018 - 04/2007
9	Infections 01/2020 - 07/2003
8	Common Variable Immunodeficiency 07/2018 - 06/2003
7	Respiratory Tract Infections (Respiratory Tract Infection) 01/2020 - 01/2014
7	Anemia 01/2019 - 11/2003
6	Hepatitis 01/2021 - 07/2006
5	Hypersensitivity (Allergy) 01/2020 - 01/2016
5	Cardiomyopathies (Cardiomyopathy) 04/2012 - 07/2002
4	Hepatomegaly 01/2021 - 01/2016
4	Non-alcoholic Fatty Liver Disease 01/2021 - 01/2012
4	Inflammation (Inflammations) 01/2020 - 01/2005
4	Iron Deficiencies 01/2019 - 11/2004
4	Insulin Resistance 01/2018 - 03/2015
3	Hypertrophy 09/2017 - 01/2016
3	Diabetes Mellitus 01/2016 - 01/2008
3	Siderosis 04/2012 - 01/2007
3	Liver Cirrhosis (Hepatic Cirrhosis) 05/2009 - 01/2007
3	beta-Thalassemia (Cooley's Anemia) 07/2007 - 03/2007
2	Splenomegaly 01/2021 - 09/2017
2	Malaria 03/2020 - 01/2020
2	Bacterial Infections (Bacterial Infection) 01/2020 - 01/2019
2	Thalassemia 09/2017 - 11/2003
2	Portal Hypertension 05/2017 - 05/2009
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017 - 03/2015
2	Porphyria Cutanea Tarda 01/2016 - 08/2007
2	Hypothyroidism 01/2016 - 01/2016
2	Breast Neoplasms (Breast Cancer) 01/2016 - 08/2007
2	Liver Failure 04/2012 - 07/2009
2	Pica (Geophagia) 02/2012 - 12/2010
2	Chronic Hepatitis C 01/2012 - 11/2003
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 11/2011 - 11/2003
2	Liver Diseases (Liver Disease) 08/2007 - 07/2006
2	Sickle Cell Anemia (Hemoglobin S Disease) 03/2007 - 05/2005
2	Hemoglobinopathies 05/2005 - 11/2003
1	Fanconi Syndrome (Syndrome, Fanconi) 07/2022
1	Acidosis 07/2022
1	Glycosuria 07/2022
1	Rheumatoid Arthritis 04/2022
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 04/2022
1	Ascites 01/2021
1	Abdominal Pain (Pain, Abdominal) 01/2021
1	Mannose-Binding Protein Deficiency 01/2019
1	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 01/2019
1	Thrombocytosis (Thrombocythemia) 01/2019
1	Thrombocytopenia (Thrombopenia) 01/2019
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019
1	Neoplasms (Cancer) 01/2019
1	Fatty Liver 08/2018

Drug/Important Bio-Agent (IBA)

62	IronIBA 06/2022 - 02/2003
31	Ferritins (Ferritin)IBA 06/2022 - 04/2003
23	Transferrin (beta 2 Transferrin)IBA 06/2022 - 01/2005
14	Immunoglobulin G (IgG)IBA 04/2022 - 06/2003
12	HLA-A Antigens (HLA-A)IBA 06/2022 - 10/2002
8	HLA Antigens (Human Leukocyte Antigens)IBA 06/2022 - 01/2005
6	Aspartate Aminotransferases (Aspartate Transaminase)IBA 06/2022 - 04/2012
6	Immunoglobulins (Immunoglobulin)IBA 04/2022 - 07/2003
6	Immunoglobulin M (IgM)IBA 01/2020 - 07/2003
6	metal transporting protein 1 (ferroportin)IBA 01/2012 - 11/2003
5	Immunoglobulin A (IgA)IBA 01/2020 - 04/2012
5	Ethanol (Ethyl Alcohol)IBA 01/2015 - 11/2003
4	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020 - 01/2016
4	Hemoglobins (Hemoglobin)IBA 01/2019 - 10/2007
4	DNA (Deoxyribonucleic Acid)IBA 08/2015 - 02/2003
3	Polysaccharides (Glycans)IBA 01/2020 - 01/2014
3	Chelating AgentsIBA 01/2020 - 03/2005
3	C-Reactive ProteinIBA 09/2017 - 01/2016
3	Alanine (L-Alanine)FDA Link 03/2016 - 04/2012
2	SodiumIBA 07/2022 - 01/2012
2	AcyltransferasesIBA 11/2020 - 08/2015
2	HepcidinsIBA 01/2019 - 01/2011
2	Alanine Transaminase (SGPT)IBA 08/2018 - 01/2014
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 01/2016
2	Immunoglobulin IsotypesIBA 05/2017 - 01/2014
2	Estrogens (Estrogen)FDA Link 01/2016 - 08/2007
2	Oral ContraceptivesIBA 01/2016 - 08/2007
2	Tamoxifen FDA LinkGeneric 01/2016 - 08/2007
2	Transaminases (Aminotransferases)IBA 06/2012 - 04/2003
2	Heme (Haem)IBA 03/2009 - 02/2008
2	5-Aminolevulinate SynthetaseIBA 01/2008 - 05/2005
2	4'-hydroxydesazadesferrithiocinIBA 07/2007 - 04/2007
2	Pharmaceutical PreparationsIBA 07/2007 - 04/2007
2	Capsules (Microcapsules)IBA 07/2007 - 04/2007
1	CalciumIBA 07/2022
1	Phosphates (Orthophosphate)IBA 07/2022
1	AcidsIBA 07/2022
1	Amino Acids FDA Link 07/2022
1	ElectrolytesIBA 07/2022
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 04/2022
1	hemozoinIBA 01/2020
1	23-valent pneumococcal capsular polysaccharide vaccineIBA 01/2020
1	Liver X ReceptorsIBA 01/2020
1	CreatinineIBA 01/2019
1	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2019

Therapy/Procedure

19	Therapeutics 04/2022 - 07/2002
5	Erythrocyte Transfusion 09/2017 - 05/2005
4	Chelation Therapy (Therapy, Chelation) 07/2007 - 01/2007
2	Drug Therapy (Chemotherapy) 01/2018 - 08/2007